All Free. The burning sensation was still present during a selective block of impulse conduction of A-fibres in myelinated fibers, which indicates that nociceptive C-fibres are activated by CFS. [6], Neurogenic itch, which is itch induced centrally but with maximum neural damage, is mostly associated with increased accumulation of exogenous opioids and possibly synthetic opioids. pruritus. There is currently little detailed data on central activation for contagious itching but it is hypothesized that a human mirror neuron system exists in which we imitate certain motor actions when we view others performing the same action. An uncomfortable sensation on the skin that causes a desire to scratch. Nilsson HJ, Levinsson A, Schouenborg J (1997). ], itch, rub, scratch - être démangé (fr) - itchy[Dérivé], wish; desire; longing; yearning; hungriness[Classe], emotion, emotions, feeling, sentiment - hope[Hyper. "Influence of genotype, dose and sex on pruritogen-induced scratching behavior in the mouse".  | Last modifications, Copyright © 2012 sensagent Corporation: Online Encyclopedia, Thesaurus, Dictionary definitions and more. itchiness. My hands and wrists suddenly began to smart and itch in a most unaccountable manner. irritation. "Epidemiology of antimalarial-induced pruritus in Africans". Increased NGF is also found in atopic dermatitis, a hereditary and non-contagious skin disease with chronic inflammation. a.) Painful electrical stimulation reduced histamine-induced itch for several hours at a maximum distance of 10 cm from the stimulated site, which suggests a central mode of action. [11], A study done by Gil Yosipovitch, Katharine Fast, and Jeffrey Bernhard showed that noxious heat and scratching were able to inhibit or decrease itch induced by transdermal iontophoresis of histamine and, most interestingly, decrease skin blood flow. itchiness. ], discomfort, irritation, soreness - irritation - irritating, irritative - brush away, pass over, rub down, wipe, wipe out - itch, rub, scratch - itch - itchy - chafe, fray, fret, rub, scratch - chafe, excoriate - abrade, abrase, corrade, rub down, rub off - grate, scrape - scrape, scratch, scratch up - scrape, skin - abrading, abrasive, scratchy[Dérivé], rub - itch - chafe, flay, graze, scrape - abraser (fr) - abrade[Nominalisation], flick, rub, whisk, wipe - itch, itchiness, itching - scratcher - mange, scab, scabies - abrasion, excoriation, graze, scrape, scratch[Dérivé], cause to be perceived - cutaneous sensation, cutaneous sensibility, dermal sensation, haptic sensation, skin sensation - infection[Hyper. An itch is a skin irritation that causes the desire to scratch.Scratch describes the action used to relieve an itch. to 'scoop'. [5], Neuropathic itch can originate at any point along the afferent pathway as a result of damage of the nervous system. tingling. eczema of the hands and arms, occurring among washerwomen. Chaucer. An explanation is that higher dosage produces more pain and the presence of pain inhibits itch thereby lowering the amount of overall scratching. CFS proves to offer a new method of combating itch by using painful electrical stimulation as it creates a long-lasting inhibitory effect, does not create any significant skin injuries, and is simple to apply. Green AD, Young KK, Lehto SG, Smith SB, Mogil JS (2006). The different substances that elicit itch upon intracutaneous injection (injection within the skin) elicit only pain when injected subcutaneously (beneath the skin). Chloroquine has been used in animal studies and in humans as a tool to study the itch mechanisms. "Mechanisms of Chloroquine-Induced Body-Scratching Behavior in Rats". ), Pruritic urticarial papules and plaques of pregnancy, "Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch", http://www.nature.com/neuro/journal/v4/n1/full/nn0101_72.html, "Specific C-receptors for itch in human skin", http://www.jneurosci.org/cgi/content/full/17/20/8003, "Noxious heat and scratching decrease histamine-induced itch and skin blood flow", http://www.nature.com/jid/journal/v125/n6/full/5603667a.html, http://en.wikipedia.org/w/index.php?title=Itch&oldid=499686195. Another word for itchy. ItchItch, n. 1. Pain evokes a withdrawal reflex which leads to retraction and therefore a reaction trying to protect an endangered part of the body. For example, responding to a local itch sensation is an effective way to remove insects on the skin. In addition, expression of neuro growth factors (NGF) can cause structural changes in nociceptors, such as sprouting. Ward L, Wright E, McMahon SB (1996). Yosipovitch G, Greaves MW, Schmelz M (2003). Even more potent was the itch in the blood of all the Darties for a real flutter. Synonyms: wound slightly ( as with the nails) scratch (v. Also, other similar mites affecting the lower animals, as the horse and ox. Judge Briscoe, and his daughter, Minnie, and (what stirred wonder to an itch almost beyond endurance) Mr. Fisbee! "Itch: more than skin deep". Scratch my back – I've got an itch. See if you can get into the grid Hall of Fame ! Dryden. In addition, it was found that patients with neuropathic pain, histamine ionophoresis resulted in a sensation of burning pain rather than itch, which would be induced in normal healthy patients. psoriasis. Depending on the cause of your itchy skin, it may appear normal, red, rough or bumpy. See More Nearby Entries ", 3.have or perceive an itch"I'm itching--the air is so dry! In a study done by Amanda Green and others, they aimed to determine itch-related genetic factors and establish a more useful animal model for itch. scratch wig. Some plant products have been found to be effective anti-pruritics, others not. Two major classes of human C-fibre nociceptors exist: mechano-responsive nociceptors and mechano-insensitive nociceptors. Each official was an adept at the art of extortion, and every palm that held a key was troubled with the itch. Oral anti-itch drugs also exist and are usually prescription drugs. What is the meaning of itch? [18] It has been hypothesized that motivational aspects of scratching include the frontal brain areas of reward and decision making. What is the meaning of itch? See under Baker. tickle. Hercogová J (2005). It's a really pure form of creativity. Sensitivity to pruritic stimuli is evenly distributed across the skin and has a clear spot distribution with similar density to that of pain. Change the target language to find translations. In studies in rats, an inverted U-shaped dose response curve to chloroquine pruritogenicity was first described by Onigbogi et al.,[8] and has been subsequently confirmed by others. The electrodes were stimulated continuously at 4 hertz per electrode, with a pulse duration of 1 millisecond, and an intensity of 0.4–0.8 milliampere lasting for 25 minutes. Synonyms for scratchy. [1], noco(i/b/d/q/u/r/p/m/k/v/f)/cong/tumr(n/e/d), sysi/epon, This entry is from Wikipedia, the leading user-contributed encyclopedia. Synonyms for 'Itch'. Add new content to your site from Sensagent by XML. Find more ways to say scratch, along with related words, antonyms and example phrases at Thesaurus.com, the world's most trusted free thesaurus. 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